1. Zajęcia dydaktyczne
    1. Bioinformatyka
    2. Modelowanie Molekularne
    3. Struktura Polimerów i Biopolimerów
    4. Wstęp do Programowania w Naukach Przyrodniczych
    5. Wspomaganie Komputerowe Pracowni Chemicznej
    6. Laboratorium Chemii i Biologii Strukturalnej
  2. Courses in English
    1. Bioinformatics
    2. Molecular Modelling

Bioinformatics

Course in English, winter semester

Bioinformatics provides tools to gather and analyse biological data, primarily sequences and structures of proteins and nucleic acids. Bioinformatics helps studying ewolution of species and to investigate protein function.

  • Bioinformatic databases:
    • of sequences (nr, UniProt, PFam, InterPro) and structures (PDB)
    • 'curated' vs 'non-curated' databases
    • non redundant and redundant databases
    • other databases and ontologies: KEGG, GeneOntology
  • Homology:ortologs, paralog and analogs
  • Sequence alignment - exact approach
    • dynamic programming algorithm
    • substitution matrix and gap penalty
    • local vs. global alignment
  • Sequence alignment: heuristics
    • blast
    • fasta